Distributions of TpG and CpA scores in 1-kb promoters. The left histograms show the distributions of TpG scores in the ascidian (A), human CpG-poor (B), and CpG island promoters (C). The right histograms show the distributions of CpA scores in the ascidian (D), human CpG-poor (E), and CpG island promoters (F). Vertical dotted lines indicate the positions of mean, i.e. 1.14, 1.24, 1.00, 1.14, 1.24, and 0.99 for (A)-(F), respectively The score 1.0 means that the observed and expected numbers of the dinucleotide are equal, suggesting no methylation effect in this case.
Okamura et al. BMC Genomics 2011 12(Suppl 3):S7 doi:10.1186/1471-2164-12-S3-S7