Relationship between average intrinsic disorder in proteins and their co-expression correlation and stability. Average percentage of intrinsic disorder in proteins as compared to the average co-expression a) correlation, and b) stability calculated over all interactions. c) Distribution of the fraction of disordered residues for proteins over varying levels of average co-expression correlation and stability. Gray regions indicate the absence of proteins for that window of correlation and stability values. Refer Figure S3 a in Additional File 1 for standard error values. Proteins that have low co-expression correlation and high co-expression stability with their interaction partners contain the highest levels of disorder.
Patil et al. BMC Genomics 2011 12(Suppl 3):S19 doi:10.1186/1471-2164-12-S3-S19