Table 1

Comparison of methylated and unmethylated promoter CGIs.

Unmethylated CpG Islands

Methylated CpG Islands

P-Value


Number of Islands

150

13

Length

1188.27±161.48

1145.92±359.79

< 1.48 x 10-11

GC Content (%)

60.76±10.34

66.44±19.34

< 1.81 x 10-2

ObsCpG/ExpCpG

1.49±0.25

1.63±0.47

< 1.81 x 10-2


Methylated and unmethylated promoter CGIs were compared by sequence for average length, GC content (%), and ObsCpG/ExpCpG ratio. P-values were determine using the Kolmogorov-Smirnov two-sample test.

Spontaneo and Cercone BMC Genomics 2011 12(Suppl 2):S10   doi:10.1186/1471-2164-12-S2-S10

Open Data