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Table 5
*Associations of 32 bimodal genes with cis-determining SNPs and reported CNV.*
Bimodality confirmed in all data sets	Gene symbol	SNP association with expression p-val^a	Kappa coeff.	# of SNPs within 200 KB	Reported CNV^b

Yes	*GSTM1*	1.20E-11	0.65	36	Yes

Yes	*HLA-DRB1*	<1E-16	0.83	119	Yes

Yes	*ERAP2*	<1E-16	0.85	94	No

Yes	*HLA-DRB5*	2.12E-14	0.86	104	Yes

Yes	*MAOA*	<1E-16	0.80	69	No

Yes	*ACTN3*	<1E-16	0.90	9	No

	MEIS2	0.04	0.17	86	No

	*TMEM70*	<1E-16	0.39	76	No

	*SLC44A5*	<1E-16	0.74	112	Yes

Yes	NR4A2	0.26	0.00	36	No

	RAD23A	0.22	0.09	13	No

	*ABCC6*	2.88E-10	0.36	59	Yes

	CHAC1	0.035	0.12	12	No

	*FLJ11151*	8.62E-7	0.43	181	No

	BACE1	0.0037	0.17	79	No

Yes	*THNSL2*	<1E-16	0.95	74	No

	PKDREJ	0.023	0.02	24	Yes

	KLRD1	0.084	0.01	61	No

	KIAA1618	0.088	0.09	63	Yes

	C19orf62	0.022	0.01	41	Yes

	MYL2	0.061	0.00	52	No

	RPL18	0.17	0.10	19	Yes

	*HLA-C*	<1E-16	0.51	153	Yes

	COX6C	0.000097	0.15	36	No

	COPS7A	0.048	0.04	47	No

	PLEKHJ1	0.048	0.14	22	Yes

	*HSPC157*	<1E-16	0.84	64	Yes

	HMGCS2	0.0026	0.25	76	Yes

	OR8H1	0.049	0.23	49	No

	CYR61	0.012	0.11	100	No

	ELOF1	0.019	0.04	32	No

	ARF1	0.065	0.12	55	Yes

^aHighest SNP association shown. All other significant SNPs are listed in Additional file 5. Apparent cis-acting eQTL are identified in bold. ^bCopy number variation (CNV) as identified in the UCSC Genome Browser.
Mason et al. BMC Genomics 2011 12:98 doi:10.1186/1471-2164-12-98

Table 5