Table 1

Pattern motifs for converted structures of sea anemone toxins obtained with SRDA("C.").

Screening line

Number of seq.

Example (sequence ID)


motif 1

C1C##C6C#CC

44

Cangitoxin (P82803), AETX-1 (P69943)

motif 2

C1C##C9C#CC#.

8

BDS-II (P59084), APETx2 (P61542)

motif 3

C8C#C*C3C#C.

8

kaliseptin (Q9TWG1), ShK (P29187)

motif 4

C8C*C#C*C3C

9

AsKC1 (Q9TWG0), APHC1 (B2G331)

motif 5

C8C#C*C1C#C#.

2

SHTX-5 (B1B5J0), Gigantoxin-1 (BAD01579)

motif 6

CC#C#CC*C1C*C.

2

AETX-2 (P69944)

motif 7

CC1C*C*C*C*C1C#.

1

PA-TX (P09949)

motif 8

CC1C#C5C*C#.

1

Neurotoxin 3 (1ANS)

motif 9

C6C*C*C*C6C#.

2

acrorhagin II (BAE46983)

motif 10

C8C3C#C.

1

Metridin (P11495)

motif 11

C#C#C#C#C#C#C#C#.

2

Acrorhagin-1 (BAE46981)

motif 12

C6C#C#C1C*C1C

3

AvTX-60A (BAD04943), PsTX-60B (P58912)

motif 13

C#C#C#C#.

1

SHTX-1/SHTX-2 (P0C7W7)

motif 0

###.

18

Equinatoxin II (P61915), Cytolysin-3 (Q9U6X1)

motif 14

##C

2

Up-1 (P0C1G1), bandaporin (BAH80315)

motif K

K > = 6 AND C < = 2

TOTAL

104


Each motif was developed from a number of toxin sequences; see some examples in the last column. Symbol # in a screening line corresponds to any digital symbol (0-9), while * designates any suitable omission.

Kozlov and Grishin BMC Genomics 2011 12:88   doi:10.1186/1471-2164-12-88

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