Comparison of RNA-seq and array profiling. (A) Correlation between the RNA-seq and microarray analysis for cells grown in rich media in hypoxic conditions. (B) Correlation between the RNA-seq and microarray analysis for the comparison of the upc2 deletion and wildtype cells grown in hypoxia. The log fold-changes of the FPKM ratio from the RNA-seq experiments is plotted on the x-axis, and the mean log fold-change from the microarray analysis is plotted on the y-axis. Each circle corresponds to a single gene; genes that are significantly differentially expressed in both microarray and RNA-seq analyses are colored in red.
Guida et al. BMC Genomics 2011 12:628 doi:10.1186/1471-2164-12-628