Table 1

QTLs from classical phenotypes overlapping with eQTLs

Chromosome

Mb

Record

Phenotype

Max LRS

Max LRS Location (Chr: Mb)


3

20-30

12958

Blood chemistry, cardiovascular system: White blood cell count of 14-week old males

19

Chr3: 28.293133

4

28-35

10410

Immune function: Antigenic activity of irradiated BXD spleen cells for Thy1+CD3+CD4+CD8- T-cell clone TGVH32

31

Chr4: 31.651725

17

25-45

11025

Infectious disease, immune function: Chlamydia psittaci (6BC) infection response (10^4 IFU ip), pathogen load in peritoneal cavity at 30 days among surviving 3-5 month males

33.6

Chr17: 31.769795

17

25-45

10466

Immune function, gastrointestinal system: Intestinal intraepithelial gamma-delta type T lymphocytes (i-IELs) in 2-6 month old adults based on receptor expression (V-gamma-7 positive, Vgamma-4 negative T cells)

33.1

Chr17: 32.068297

17

25-45

10236

Proliferation of JTL-G12 cells (T cell clone) with 50 ug/ml GAT (Glu60, Ala30, Tyr10)

24.5

Chr17: 32.068297

17

25-45

10238

Proliferation of JTL-G12.8 (Tcell clone) with 50 ug/ml GAT (Glu60, Ala30, Tyr10)

26.7

Chr17: 32.068297

17

25-45

10441

Anti-F antigen (liver protein) titer, experiment 1

19.1

Chr17: 26.950946

17

25-45

12672

Infectious disease, immune function: Ectromelia virus survival over two weeks after a 90 pfu intranasal inoculation, males and females between 40 and 150 days of age, residuals corrected for sex, age, and body weight

19.5

Chr17: 31.179359


Alberts et al. BMC Genomics 2011 12:610   doi:10.1186/1471-2164-12-610

Open Data