Additional file 5.

'Additional Results and Discussion': This file contains additional results on: Trans-eQTLs mapping in Treg and Th cells, the analysis of candidate genes in trans-eQTL intervals, and the analysis of autoimmune traits. Also, the file contains additional discussion points on Treg-specifc genes, the analysis of the interval on chromosome 2 found to regulate expression of Nrp1, analysis of an interval on chromosome × regulating expression of Klrb1f/A630024B12Rik (killer cell lectin-like receptor subfamily B member 1F) and Ctla4 (cytotoxic T-lymphocyte-associated protein 4), the analysis of known Treg functional genes for possible cis- or trans-eQTLs, and the analysis of the QTLs interval chromosome 4 associated with autoimmune traits.

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Alberts et al. BMC Genomics 2011 12:610   doi:10.1186/1471-2164-12-610