Cis and trans ceQTLs. Every point represents the regulation of a gene (y-axis) by a marker (x-axis). White streaks are centromeric regions. Horizontal marginal shows number of genes regulated in trans by each loci. The probability that a marker would regulate more than 4 genes is 0.31 (FDR < 0.4, light blue line) and more than 7 genes is 0.008 (FDR < 0.01, red line). Vertical marginal illustrates number of trans ceQTLs regulating each gene. The likelihood that a gene is regulated by more than 16 trans ceQTLs is 0.29 (FDR < 0.3, light blue line) and more than 23 is 0.01 (FDR < 0.01, red line). Both highly regulatory loci and highly regulated genes are evident.
Wang et al. BMC Genomics 2011 12:562 doi:10.1186/1471-2164-12-562