Table 4

Unique genes with decreased expression in spleen after SGIV infection

swissprot_annotation

species

Expression in control

Expression in infection

Fisher p_value


H-2 class II histocompatibility antigen

Mus musculus

11365

1044

0

Glutathione peroxidase 1

Bos taurus

3469

509

0

Endothelial differentiation-related factor 1

Xenopus laevis

5830

172

0

Inositol-3-phosphate synthase 1-A

Xenopus laevis

1618

148

0

Palmitoyl-protein thioesterase 1

Mus musculus

6570

92

0

Proteasome subunit beta type-2

Bos taurus

2244

84

0

Cytochrome c oxidase subunit 1

Gadus morhua

7690

66

0

Myosin light polypeptide 6

Rattus norvegicus

1733

65

0

Eukaryotic translation initiation factor 3 subunit

Danio rerio

1765

60

0

Gamma-interferon-inducible lysosomal thiol reductase

Homo sapiens

2962

55

0

Mid1-interacting protein 1-like

Danio rerio

3667

54

0

Elongation factor 1-gamma

Carassius auratus

1821

51

0

Plastin-2

Danio rerio

1777

51

0

ribosomal protein S8

Rattus norvegicus

1737

48

0

Stefin-C

Bos taurus

1991

46

0

Complement C1q subcomponent subunit A

Bos taurus

1511

43

0

ribosomal protein L22

Xenopus tropicalis

2286

33

0

ribosomal protein L18

Oreochromis niloticus

1598

29

0

Nucleolar protein 16

Tetraodon nigroviridis

1949

377

9.53E-251

Transcription initiation factor TFIID

Pongo abelii

2123

469

6.58E-246

Transforming protein RhoA

Rattus norvegicus

1258

202

4.46E-184

Peroxiredoxin

Cynops pyrrhogaster

2563

982

7.87E-157

Myosin regulatory light chain 2

Gallus gallus

5634

3124

2.64E-154

Heat shock 70 kDa protein

Canis familiaris

612

31

7.54E-140

Ras-related C3 botulinum toxin substrate 2

Bos taurus

928

167

1.56E-126

SH3 domain-containing protein

Mus musculus

609

48

1.33E-123

Rab GDP dissociation inhibitor beta

Rattus norvegicus

602

48

9.70E-122

Cystatin-A5

Sus scrofa

2339

994

4.94E-120

Radixin

Mus musculus

675

77

8.53E-119

Interferon-inducible GTPase 1

Homo sapiens

805

181

4.16E-93

C-X-C chemokine receptor type 4

Papio anubis

1929

851

1.51E-92

AIG2-like domain-containing protein

Danio rerio

617

128

1.59E-76

Major complex class I-related gene

Mus musculus

1058

366

1.83E-76

Thioredoxin-dependent peroxide reductase,

Homo sapiens

769

209

1.20E-74

Death-associated protein-like 1-B

Xenopus laevis

1417

638

9.05E-66

RING finger protein 10

Mus musculus

277

24

3.52E-55

Mannan-binding lectin serine protease 2

Mus musculus

2177

1249

6.20E-55

GTP-binding nuclear protein

Salmo salar

3669

2432

9.56E-54

Regulator of G-protein signaling 8

Danio rerio

1206

639

6.61E-39

Matrix metalloproteinase-9

Homo sapiens

199

21

2.33E-37

Bleomycin hydrolase

Gallus gallus

418

125

2.50E-37

Src kinase-associated phosphoprotein 2

Takifugu rubripes

257

47

8.27E-36

Interferon-induced protein 44-like

Mus musculus

352

94

1.44E-35

Protein disulfide-isomerase A4

Rattus norvegicus

191

21

2.56E-35

Macrophage mannose receptor 1

Homo sapiens

257

49

8.14E-35

Prothymosin alpha-B

Danio rerio

186

21

4.75E-34

Ubiquitin-conjugating enzyme E2

Drosophila melanogaster

344

97

6.36E-33

Myosin-8

Canis familiaris

1023

547

1.60E-32

cAMP-responsive element-binding protein

Danio rerio

684

312

8.58E-32

Programmed cell death protein 10

Mus musculus

383

123

1.42E-31

Peroxisomal membrane protein 2

Bos taurus

612

267

3.46E-31

E3 ubiquitin-protein ligase

Homo sapiens

220

41

2.02E-30

Myoferlin

Xenopus tropicalis

262

62

4.71E-30

Ras-related protein Rab7

Gossypium hirsutum

223

50

6.44E-27

Dynactin subunit 6

Homo sapiens

242

61

2.40E-26

protease regulatory subunit 4

Rattus norvegicus

229

55

4.43E-26

Interferon regulatory factor 1

Gallus gallus

446

183

1.06E-25

Hephaestin-like protein 1

Mus musculus

276

88

2.05E-23

Galectin-8

Homo sapiens

158

29

1.39E-22

Apoptosis-associated speck-like protein

Danio rerio

497

233

2.41E-22


Huang et al. BMC Genomics 2011 12:556   doi:10.1186/1471-2164-12-556

Open Data