Table 3

Unique genes with increased expression in spleen after SGIV infection

Gene name

species

expression in normal

Expression in infection

Fisher p_value


Profilin-2

Rattus norvegicus

305

29051

0

60S ribosomal protein

Homo sapiens

251

23569

0

Eotaxin

Mus musculus

3169

17689

0

Granulins

Rattus norvegicus

1141

15720

0

Leukocyte cell-derived chemotaxin-2

Mus musculus

4809

10637

0

Thioredoxin

Ictalurus punctatus

542

7343

0

Saposin-C

Cavia porcellus

43

5116

0

Cystatin-B 1

Macaca fuscata

92

4388

0

Perforin-1

Mus musculus

105

4097

0

Scavenger receptor cysteine-rich type 1 protein

Canis familiaris

911

3958

0

Eukaryotic translation initiation factor 4 gamma 2

Gallus gallus

573

3829

0

Gamma-glutamyl hydrolase

Homo sapiens

133

2638

0

Legumain

Bos taurus

445

2572

0

Proteasome subunit alpha type-7

Carassius auratus

35

2452

0

Glyceraldehyde 3-phosphate dehydrogenase,

Danio rerio

103

1983

0

Transcription factor BTF3

Mus musculus

83

1770

0

Src-like-adapter

Mus musculus

84

1371

2.02E-303

Keratin 8

Gallus gallus

182

1586

5.86E-283

Galectin-3-binding protein B

Danio rerio

450

2187

8.23E-277

SUMO-conjugating enzyme

Xenopus tropicalis

137

1307

8.94E-243

C-C motif chemokine 18

Macaca mulatta

282

1667

3.00E-242

Galectin-3-binding protein A

Danio rerio

371

1747

3.37E-216

Hemoglobin subunit beta-1

Pseudaphritis urvillii

241

1383

1.38E-197

Keratin 18

Oncorhynchus mykiss

1661

3701

7.37E-180

Eukaryotic translation initiation factor 3

Bos taurus

67

844

4.27E-174

Cytochrome b

Tropheus moorii

6544

9945

1.29E-163

Natural killer cell protease 1

Rattus norvegicus

227

1138

1.95E-148

T-complex protein 1

Gallus gallus

50

669

6.61E-141

RNA-binding protein 5

Xenopus tropicalis

45

605

7.97E-128

Cathepsin H

Sus scrofa

391

1347

3.79E-125

Beta-2-glycoprotein 1

Bos taurus

433

1389

7.97E-119

Dipeptidyl peptidase 1

Bos taurus

55

586

1.36E-114

Proto-oncogene vav

Mus musculus

98

693

8.51E-113

Proteasome subunit alpha type-4

Homo sapiens

684

1761

2.56E-111

Actin-related protein 2/3 complex subunit 5

Mus musculus

90

656

1.35E-108

Proteasome subunit beta type-6-B like

Salmo salar

469

1361

8.49E-103

RING-box protein 2

Mus musculus

42

497

3.76E-101

NADH-ubiquinone oxidoreductase chain 1

Carassius auratus

330

1102

2.68E-99

Phospholipid hydroperoxide glutathione peroxidase

Sus scrofa

590

1527

1.66E-97

Retinol-binding protein 1

Bos taurus

164

767

1.80E-95

NudC domain-containing protein 2

Rattus norvegicus

81

576

3.36E-94

Lysozyme g

Epinephelus coioides

164

742

5.02E-90

Voltage-gated hydrogen channel 1

Danio rerio

217

742

4.09E-69

Ubiquitin-like modifier-activating enzyme 5

Xenopus laevis

179

670

8.17E-69

LRR and PYD domains-containing protein 1

Homo sapiens

205

714

6.02E-68

Cytochrome c oxidase subunit 6B1

Tarsius syrichta

60

395

2.33E-62

Ig lambda chain

Homo sapiens

31

315

2.99E-61

Interleukin-8

Equus caballus

155

572

4.14E-58

Fibroleukin

Homo sapiens

611

1281

3.75E-56

Rho GDP-dissociation inhibitor 1

Macaca fascicularis

325

844

4.69E-55

Ependymin

Notemigonus crysoleucas

70

386

5.52E-55

Fucolectin-4

Anguilla japonica

1519

2434

1.29E-50

Complement factor H

Homo sapiens

131

459

1.88E-44

Eukaryotic initiation factor 4A-III

Xenopus tropicalis

56

282

4.32E-38

Cysteine and glycine-rich protein 2

Mus musculus

61

290

1.68E-37

Proliferating cell nuclear antigen

Haplochromis burtoni

237

575

3.64E-34

Secernin-3

Danio rerio

64

277

2.42E-33

Ubiquitin-conjugating enzyme E2

Mus musculus

74

286

4.09E-31

Heat shock cognate 71 kDa protein

Oryzias latipes

25

181

8.31E-31


Huang et al. BMC Genomics 2011 12:556   doi:10.1186/1471-2164-12-556

Open Data