Figure 3.

Trans-fat feeding induces sex-specific alterations in cardiac gene expression. A: Bar chart indicates differences in numbers of significant DEGs affected by the TFA diet in males and females, * P < 0.001 by Fisher's exact test. B-E: Sex-specific differences in functional ontology of genes deregulated by the TFA diet. Pie charts show the number of genes that were upregulated in males B; downregulated in males C; upregulated in females D; downregulated in females E. Functional categories of DEGs were obtained using GO annotations from DAVID.