Lateral transfer of TF genes within the E. coli - Shigella clade. TFs were separated into three main groups: global regulators, neighbour regulators and other regulators. TF-encoding gene sets that yielded proteins trees that were discordant with the MRP reference tree and/or were ORB+ were classified as LGT, whereas gene sets that yielded concordant protein trees and had no recombination breakpoints within the gene boundaries were classified as non-LGT. The LGT genes were further divided into two groups: ORB+ and ORB-.
Skippington and Ragan BMC Genomics 2011 12:532 doi:10.1186/1471-2164-12-532