Table 3

Non-synonymous SNPs identified in BCG Mexico compared with BCG Pasteur 1173P2 and BCG Tokyo 172.

SNP

Location1

Gene

Change

In comparison with BCG


1

39256

BCGMEX_0037c

NS

Pasteur

2

89198

BCGMEX_0084

NS

Tokyo

3

338587

PE_PGRS4

NS

Tokyo

4

535543

sigK

NS

Tokyo

5

562401

pcaA

NS

Tokyo

6

582595

regX3

NS

Tokyo

7

585522

BCGMEX_0506c

NS

Tokyo and Pasteur

8

644544

BCGMEX_0568

NS

Tokyo

9

739067

mmaA3

NS

Tokyo

10

1165878

BCGMEX_1072c

NS

Tokyo

11

1294737

narJ

NS

Pasteur

12

1465719

BCGMEX_1346c

NS

Tokyo

13

1908146

PPE22

NS

Pasteur

14

1987564

BCGMEX_1787c

NA

Pasteur

15

2171779

BCGMEX_1957

NS

Tokyo and Pasteur

16

2261942

pks12

NS

Pasteur

17

2268073

pks12

NS

Pasteur

18

2599245

hrcA

NS

Tokyo

19

2625029

BCGMEX_2390

NA

Tokyo and Pasteur

20

2637892

PE_PGRS41

NS

Tokyo

21

2839572

BCGMEX_2587c

NS

Pasteur

22

3294834

ilvN

NS

Pasteur

23

3433045

PPE50

NS

Tokyo

24

3433175

PPE50

NS

Tokyo

25

3537078

BCGMEX_3256

NS

Tokyo

26

3592845

BCGMEX_3305c

NS

Tokyo

27

3674969

sdhB

NS

Tokyo

28

3785919

BCGMEX_3469

NS

Tokyo

29

4015927

hpt

NS

Tokyo

30

4059882

BCGMEX_3724

NA

Pasteur

31

4069095

BCGMEX_3734

NS

Tokyo

32

4075693

ponA2

NS

Tokyo and Pasteur

33

4087843

BCGMEX_3752

NS

Tokyo


1Locations and names of affected genes follow BCG Mexico 1931; bold text indicates previously reported SNPs; NS = non-synonymous; NA = not annotated

Orduña et al. BMC Genomics 2011 12:493   doi:10.1186/1471-2164-12-493

Open Data