Table 1

Region of difference (RD) profiles in BCG Mexico strains.

BCG

Profile of regions of difference

Substrains

RD1

RD2

RD8

RD14

RD16

RD18

RDD/G

IS6110

DU2


Mexico

seed lot 1931

-

-

+

+

+

-

+

+

IV

Phipps

-

-

+

+

+

-

+

+

IV

Tice

-

-

+

+

+

-

+

+

IV

Mexico

seed lot 1988

-

-

+

+

+

+

-

+

III

Mexico

vaccine 1997

-

-

+

+

+

+

-

+

III

Danish 1331

-

-

+

+

+

+

-

+

III


The symbol (-) indicates the loss of a region in the genome of a given strain, whereas the symbol (+) indicates the presence of the region. RD = region of difference; IS6110 = insertion sequence IS6110 (presence of a single copy); DU = tandem duplication.

Orduña et al. BMC Genomics 2011 12:493   doi:10.1186/1471-2164-12-493

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