Figure 6.

Structural analysis of CpCDPK4. (A) Overall view of CpCDPK4 [PDB: 3HKO] with the zinc finger and β-mesh insert highlighted in lime. (B) Zn-finger of CpCDPK4 is shown with the residues involved in zinc binding noted. (C) Overlay of aligned views of CpCDPK4 with the C-terminus of the KD and entire CAD of TgCDPK1 (for visual clarity the N-terminal portion of the KD is not shown) in grey [PDB: 3KU2]. (D) An overall structural comparison of CpCDPK4 (teal/lime) and PKC-ι (salmon/magenta) [PDB:3AX8] with the C-terminal tail (from K531) highlighted in magenta and a circle indicating its overlap with CpCDPK4. (E) An overall structural comparison of CpCDPK4 (teal/lime) and human CLK1 (pale yellow) [PDB:1Z57]. (F) An overall structural comparison of CpCDPK4 (teal/lime) and human SRPK (beige) [PDB:1WBP].

Artz et al. BMC Genomics 2011 12:478   doi:10.1186/1471-2164-12-478
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