Figure 3.

Distribution of the 2,145 paternal and 2,145 maternal recombination events across all human autosomal chromosomes (A), chromosome 1 (B) and chromosome 6 (C). (A) The distribution of the numbers of the paternal (blue bar) and maternal (red bar) recombination events across autosomal chromosomes. (B) The number of recombination sites for chromosome 1 was calculated using a window width of 1 Mb. The middle and lower panel of the Figure 3B are the Marshfield recombination map and Icelandic recombination map, respectively. The maternal (red) and paternal (blue) genetic distance for each 1-Mb window was calculated on the basis of the SNP position information provided by Affymetrix. We assumed a constant crossover rate between two adjacent SNP markers. The physical position and the chromosome ideogram are shown on the top and bottom of the figure, respectively. (C) The regression lines for maternal (red) and paternal (blue) crossover rates corresponding to the distance from the centromere are shown, using chromosome 6 as an example. The slope was significantly different from zero in the p arm of male but not in female chromosomes. In contrast, both genders showed a significant correlation in the number of recombination sites towards the telomere of the q arm. The chromosomal regions without any SNP site in the Affymetrix Genome-Wide Human SNP 6.0 arrays are marked as gray blocks.

Lee et al. BMC Genomics 2011 12:434   doi:10.1186/1471-2164-12-434
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