Table 1

In vivo evaluation of Babesia bovis attenuation

Inoculated strain

T2Bo_vir

T2Bo_att

L17_vir

L17_att


# of animals

12

18

12

18

Average age of animal (mth)

16.5

15.5

17

16

# of animals requiring treatment*

12/12

0/18

12/12

0/18


* treatment criteria include one of the following. Hyperthermia > 41°C for 3 consecutive days, percent parasitemia > 0.5%, hematocrit < 15% and neurological signs such as ataxia, excess salivation, head pressing, lateral head torsion and recumbency w/. fully extended head. Vir, virulent phenotype; att, attenuated phenotype; T2Bo, Tex strain; L17, Argentina strain.

Lau et al. BMC Genomics 2011 12:410   doi:10.1186/1471-2164-12-410

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