Open Access Research article

Attenuation of virulence in an apicomplexan hemoparasite results in reduced genome diversity at the population level

Audrey OT Lau1*, Ananth Kalyanaraman2, Ignacio Echaide3, Guy H Palmer1, Russell Bock4, Monica J Pedroni1, Meenakshi Rameshkumar2, Mariano B Ferreira3, Taryn I Fletcher45 and Terry F McElwain1

Author Affiliations

1 Programs in Genomics and Vector-borne Diseases, Department of Veterinary Microbiology & Pathology and Paul G. Allen School for Global Animal Health, College of Veterinary Medicine, Washington State University, Pullman, WA 99164-7040, USA

2 School of Electrical Engineering and Computer Science, Washington State University, Pullman WA 99164-2752, USA

3 Instituto Nacional Tecnologia Agropecuaria, 2300 Rafaela, Santa Fe, Argentina

4 Tick Fever Centre, Biosecurity, Department of Primary Industries and Fisheries, 280 Grindle Road, Wacol, Qld. 4076, Australia

5 Department of Medicine, Imperial College London, South Kensington Campus, London SW7 2AZ, UK

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BMC Genomics 2011, 12:410  doi:10.1186/1471-2164-12-410

Published: 12 August 2011

Additional files

Additional file 1:

Table s1 Sequencing related information for the Babesia bovis strains. Additional sequencing information showing the coverages of the six B. bovis genomes. Each genome coverage is calculated relative to the size of the T2Bo_vir genome as the reference, which is 8.3 Mbp. Table s2. Contig distribution by chromosome of the three Babesia bovis strain pairs. This table illustrates the total number of assembled contigs of each genome and their chromosomal distributions of the six B. bovis strains. Table s3. List of candidate genes for re-sequencing. Candidate genes that required re-sequencing after comparative gene analysis among all six B. bovis strains was completed.

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