Open Access Highly Accessed Research article

Genome-wide survey of yeast mutations leading to activation of the yeast cell integrity MAPK pathway: Novel insights into diverse MAPK outcomes

Patricia Arias, Sonia Díez-Muñiz, Raúl García, César Nombela, José M Rodríguez-Peña* and Javier Arroyo

Author Affiliations

Departamento de Microbiología II, Facultad de Farmacia, Universidad Complutense de Madrid, IRYCIS, 28040 Madrid, Spain

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BMC Genomics 2011, 12:390  doi:10.1186/1471-2164-12-390

Published: 2 August 2011

Additional files

Additional file 1:

Complete set of yeast mutants with increased levels of Slt2 phosphorylation. Representative Western blot experiments of yeast mutants in which MAPK Slt2 was constitutively activated are shown.

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Additional file 2:

Yeast mutant strains resistant to nourseothricin without increased levels of Phospho-Slt2. Functional information on the genes whose disruption leads to antibiotic resistance without detectable Slt2 phosphorylation is shown.

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