Table 5

Overview of candidate virulence factors detected in the C. ulcerans genomes

ID in 809

ID in BR-AD22

Gene

Proposed function of deduced protein

LP×TGa


CULC809_00177

-

rbp

Ribosome-binding protein

none

CULC809_01974

CULC22_02125

cppb

Corynebacterial protease CP40b

none

CULC809_00040

CULC22_00038

pld

Phospholipase D

none

CULC809_01949

CULC22_02103

spaF

Surface-anchored protein (pilus subunit)

LPKTG

CULC809_01950

CULC22_02104

spaE

Surface-anchored protein (pilus subunit)

LPLTG

CULC809_01952

CULC22_02106

spaD

Surface-anchored protein (pilus subunit)

LPMTG

CULC809_01979

CULC22_02130

spaC

Surface-anchored protein (pilus subunit)

LPLTG

CULC809_01980

CULC22_02131

spaB

Surface-anchored protein (pilus subunit)

LARTG

CULC809_01133

CULC22_01148

rpfI

Rpf interacting protein

none

CULC809_01521

CULC22_01537

cwlH

Cell wall-associated hydrolase

none

CULC809_00434

CULC22_00437

nanH

Sialidase precursor (neuraminidase H)

none

CULC809_00509

CULC22_00515

vsp1

Venome serine protease

none

CULC809_01964

-

vsp2

Venome serine protease

none

CULC809_01848

CULC22_02007

tspA

Trypsin-like serine protease

none


a Predicted LPxTG motif used for anchoring of the protein to the cell wall

b Data presented in this manuscript indicates a function as endoglycosidase. The gene should therefore be renamed as ndoE.

Trost et al. BMC Genomics 2011 12:383   doi:10.1186/1471-2164-12-383

Open Data