Open Access Highly Accessed Research article

Genomic comparison of multi-drug resistant invasive and colonizing Acinetobacter baumannii isolated from diverse human body sites reveals genomic plasticity

Jason W Sahl1, J Kristie Johnson2, Anthony D Harris3, Adam M Phillippy45, William W Hsiao1, Kerri A Thom3 and David A Rasko1*

Author Affiliations

1 Department of Microbiology, Institute for Genome Sciences, 801 W. Baltimore Street, Baltimore, MD, 21201, USA

2 Department of Pathology, University of Maryland Medical Center N2W69, Baltimore, MD, 21201, USA

3 Division of Genomic Epidemiology and Clinical Outcomes, Department of Epidemiology and Public Health, 685 W. Baltimore Street MSTF 330, Baltimore, MD, 21201, USA

4 National Biodefense Analysis and Countermeasures Center, 110 Thomas Johnson Drive, Suite 400, Frederick, MD, 21702, USA

5 Center for Bioinformatics and Computational Biology, 3125 Biomolecular Sciences Bldg, University of Maryland, College Park, MD, 20742, USA

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BMC Genomics 2011, 12:291  doi:10.1186/1471-2164-12-291

Published: 4 June 2011

Additional files

Additional file 1:

A. baumannii genomes and isolation sources. A description of published genomes used for comparative genomics in the present study

Format: XLS Size: 24KB Download file

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Additional file 2:

Genome Assembly Statistics. Assembly statistics for the 3 genomes sequenced in this study

Format: XLSX Size: 42KB Download file

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Additional file 3:

Pulsed field gel electrophoresis (PFGE) profiles. A picture that shows PFGE profiles of the three strains sequenced in this study

Format: BMP Size: 78KB Download file

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Additional file 4:

BLAST score ratio analysis. A table of unique, divergent, and unique gene numbers as identified by blast score ratio (BSR) analysis

Format: XLS Size: 19KB Download file

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Additional file 5:

UMB001 unique genes. A table of unique genes identified in UMB001, based on a BSR value of less than 0.4

Format: XLS Size: 29KB Download file

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Additional file 6:

UMB002 unique genes. A table of unique genes identified in UMB002, based on a BSR value of less than 0.4

Format: XLS Size: 40KB Download file

This file can be viewed with: Microsoft Excel Viewer

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Additional file 7:

UMB003 unique genes. A table of unique genes identified in UMB003, based on a BSR value of less than 0.4

Format: XLS Size: 56KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 8:

Protein alignment of a conserved, A. baumannii-specific, hypothetical protein. Multiple sequence alignment of a conserved peptide identified in this study for all sequenced A. baumannii isolates

Format: TIFF Size: 859KB Download file

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