Table 3

Transcripts regulated by 2 μg Se/g diet

Genbank Accession

Gene Symbol

Gene Title

Fold Change1

adj P-value2

Nrf2 Target3


NM_017214

Rgs4

regulator of G-protein signaling 4

3.03

0.005

X

NM_022543

Ccdc80

coiled-coil domain containing 80

2.14

0.02

XM_001069576

RGD1560666

Similar to KIAA1280 protein

1.80

0.02

NM_001127580

Oxct1

3-oxoacid CoA transferase 1

1.64

0.02

NM_031147

Cirbp

cold inducible RNA binding protein

-1.83

0.02

BE107169

EST

UI-R-BS1-ayq-f-06-0-UI.s1

1.70

0.03

- - - - - - - - - - - - - - - - - - - - - - - - -

NM_001009965

Tsku

Tsukushin

2.30

0.13

X

NM_001011901

Hsph1

heat shock 105 kDa/110 kDa protein 1

1.68

0.13

NM_012886

Timp3

TIMP metallopeptidase inhibitor 3

1.68

0.13

AA945268

EST

EST200767

-3.25

0.19

NM_001164396

RGD1564865

similar to 20-alpha-hydroxysteroid dehydrogenase

-2.14

0.13


Transcripts that were significantly (above the dashed line, P < 0.05) or nearly significantly (below the dashed line, 0.05 < P < 0.2) differentially expressed in liver from rats fed 2 μg Se/g diet compared to 0.24 μg Se/g diet. 1Fold changes determined by analysis of RMA expression data with the Limma package in R software, 2P-values were adjusted for multiple testing, 3Genes known to be Nrf2 targets, determined as described in the text.

Raines and Sunde BMC Genomics 2011 12:26   doi:10.1186/1471-2164-12-26

Open Data