5 μg Se/g diet elicits a unique transcriptional effect. Unsupervised hierarchical clustering with RMA generated expression values for the 667 unique Se-specific transcripts (Figure 5). Columns represent liver expression from individual rats fed 0, 0.08, 0.24, 0.8, 2 and 5 μg Se/g diet. Rows represent probe sets. RMA gene expression is shown using the indicated pseudocolor scale from -8X (green) to +8X (red) relative to values for rats fed 0.24 μg Se/g. Clusters that are up-regulated by 2 and 5 μg Se/g diet are highlighted in red and the cluster down-regulated by 2 and 5 μg Se/g diet is highlighted in green.
Raines and Sunde BMC Genomics 2011 12:26 doi:10.1186/1471-2164-12-26