Additional file 6.

Phylogenetic analysis of the STE group. Amino acid sequences of the catalytic domain of the STE proteins of S. mansoni (blue labels), C. elegans, D. melanogaster, S. cerevisiae, H. sapiens, and B. malayi were used to construct a distance-based phylogenetic tree using PHYLIP programs. Bootstrap values (1000 replicates) equal or higher than 80% are indicated (‚óŹ) as cutoff values to support the family/subfamily classification. Functional classification is indicated individually in the protein labels. Protein families are highlighted by the vertical bars and include: STE11 (MAP3K (MAP kinase kinase kinase) genes), STE20 (MAP4K (MAP kinase kinase kinase kinase) genes), STE7 (MAP2K (MAP kinase kinase) genes).

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Andrade et al. BMC Genomics 2011 12:215   doi:10.1186/1471-2164-12-215