Table 2

Gene ontologies with differentially expressed genes in bone marrow adipocytes

Functional Group

Enrichment Score*

P value**

% genes in group present


Biological process

4.39

0.01

18.10

Cellular

40.9

<0.001

21.9

Immune system

18.36

<0.001

31.7

Metabolic

16.67

<0.001

20.7

Oxidation reduction

37.36

<0.001

30.52

Lipid

23.63

<0.001

34.7

Carbohydrate

7.41

<0.001

28.05

Developmental

4.3

0.01

19.71

Adipocyte differentiation

18.3

<0.001

47.27

Brown

31.44

<0.001

74.07

White

8.46

<0.001

71.43

Cellular component

3.55

0.03

17.97

Molecular component

1.80

0.17

17.91


A selection of genes generated from ANOVA analysis was assigned to biologically meaningful gene ontology (GO) categories using GO enrichment analysis (Partek® Genome Suite software, version 6.3). Listed are groups of gene-associated biological processes in bone marrow adipocytes compared with epididymal adipocytes (fold change cut off is 2.0). *A high value of enrichment score indicates that the functional group is over-represented in the gene list. **P value is the -log p-value of a Chi-square test.

Liu et al. BMC Genomics 2011 12:212   doi:10.1186/1471-2164-12-212

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