Representation of each PKS (polyketide synthase) and NRPS (nonribosomal peptide synthetase) gene cluster discovered on the genome of B. rhizoxinica. Arrows represent ORFs and indicate direction of transcription, circles represent domains of deduced NRPS enzymes. A = adenylation domain responsible for recognition and activation of the amino acids. C = condensation domain (catalyzes the peptide bond formation). T = peptidyl carrier protein (carries the growing peptide chain bond as a thioester.
Lackner et al. BMC Genomics 2011 12:210 doi:10.1186/1471-2164-12-210