Table 2

Significant KEGG identifiers detected based on the differentially expressed transcripts in cluster 2 for the acute phase response to E. coli infection*

KEGG ID

P value

Odds Ratio

Exp Count

Count

Size

Term

830

0.00011

19.46957

0.257269

4

24

Retinol metabolism

71

0.002574

12.51056

0.278708

3

26

Fatty acid metabolism

1100

0.016481

2.126324

6.817621

13

636

Metabolic pathways

61

0.021326

93.55556

0.021439

1

2

Fatty acid biosynthesis

980

0.029004

8.222903

0.267988

2

25

Metabolism of xenobiotics by cytochrome P450

561

0.031206

7.879108

0.278708

2

26

Glycerolipid metabolism

982

0.035802

7.270856

0.300147

2

28

Drug metabolism - cytochrome P450

*A hypergeometric gene set enrichment test was performed based on cluster 2 of the contrast T24 vs. C24. Overrepresentation of gene sets defined by the KEGG database was tested using the Fisher's exact test. A gene set was considered significant if P < 0.05.

Buitenhuis et al. BMC Genomics 2011 12:130   doi:10.1186/1471-2164-12-130