Table 2

Genes exhibiting altered expression by the treatment with cytokines alone and in combination with HNF4α shRNA.

Cut-off

Cytokine only1

HNF4 shRNA+Cytokines2

Total


Additive

Interactive

Total


FDR < 0.01

635

1065

502

1567

2202

2-fold

78

223

296

519

597


Cytokine only1 (Category B) indicates that gene expressions are significantly changed by cytokines, but not by HNF4α shRNA. HNF4 shRNA+Cytokines2 indicate that gene expressions are significantly changed by both HNF4α shRNA and cytokines, including the additive (Category C) and interactive (Category D) effects.

Wang et al. BMC Genomics 2011 12:128   doi:10.1186/1471-2164-12-128

Open Data