Table 1

Genes exhibiting altered expression by the treatment with HNF4α shRNA alone and in combination with cytokines.

Cut-off 1

HNF4 shRNA only2

HNF4 shRNA+Cytokines3

Total


Additive

Interactive

Total


FDR < 0.01

3606

1065

502

1567

5173

2-fold

878

223

296

519

1397


Two methods of cut-off 1, FDR (false discovery rate) and 2-fold changes compared to untreated controls, are shown. HNF4 shRNA only2 (Category A) denotes that gene expressions are significantly changed by HNF4α shRNA, but not by cytokines. HNF4 shRNA+Cytokines3 indicate that gene expressions are significantly changed by both HNF4α shRNA and cytokines, including the additive (Category C) and interactive (Category D) effects.

Wang et al. BMC Genomics 2011 12:128   doi:10.1186/1471-2164-12-128

Open Data