Table 2

Gene ontology (GO) biological processes related with immune, inflammatory or hypersensitivity responses commonly enriched with the genes differentially expressed in BALB/c mice in response to BLG, OVA and PNA sensitizations.

BLG Sensitized

OVA Sensitized

PNA Sensitized


GO Biological Processes

GO ID

Genes

Fisher's Exact P-Value

Genes

Fisher's Exact P-Value

Genes

Fisher's Exact P-Value


Response to stimulus

50896

100

0.005

50

0.011

50

0.002


Actin filament-based process

30029

22

0.011

11

0.041

12

0.009


Cytokine and chemokine mediated signaling pathway

19221

10

0.000

4

0.038

5

0.006


Acute inflammatory response

2526

9

0.001

6

0.001

5

0.004


Humoral immune response

6959

8

0.001

6

0.001

5

0.002


Regulation of actin filament depolymerization

30834

6

0.011

4

0.012

5

0.001


Actin filament depolymerization

30042

6

0.011

4

0.012

5

0.001


Humoral immune response mediated by circulating immunoglobulin

2455

6

0.001

3

0.024

3

0.019


Negative regulation of actin filament depolymerization

30835

5

0.028

4

0.008

5

0.001


Phagocytosis

6909

5

0.043

4

0.012

3

0.049


Positive regulation of defense response

31349

4

0.044

4

0.003

3

0.019


Positive regulation of endocytosis

45807

4

0.025

3

0.016

3

0.012


Positive regulation of response to external stimulus

32103

4

0.034

3

0.020

3

0.015


Positive regulation of inflammatory response

50729

3

0.038

3

0.005

3

0.004


Myeloid leukocyte mediated immunity

2444

3

0.026

3

0.003

2

0.032


Positive regulation of phagocytosis

50766

3

0.026

2

0.038

2

0.032


Regulation of phagocytosis

50764

3

0.026

2

0.038

2

0.032


Positive regulation of immunoglobulin mediated immune response

2891

3

0.009

2

0.019

2

0.016


Regulation of immunoglobulin mediated immune response

2889

3

0.009

2

0.019

2

0.016


Positive regulation of inflammatory response to antigenic stimulus

2863

3

0.016

2

0.028

2

0.023


Positive regulation of B cell mediated immunity

2714

3

0.009

2

0.019

2

0.016


Regulation of B cell mediated immunity

2712

3

0.009

2

0.019

2

0.016


Husain et al. BMC Genomics 2011 12:12   doi:10.1186/1471-2164-12-12

Open Data