Overview of genome resequencing and SNP allele determination. (A) 454 GS FLX sequencing technology was used for shotgun genome sequencing to fine-map crossovers and other structural variants in 2 clonal progeny lines of P. falciparum. (B) WGS reads of the progeny genomes as well as the WGS reads from the parent genomes  were mapped to the common reference sequence (strain 3D7, PlasmoDB 5.4 ). (C) High quality SNPs (see methods) captured in parent and progeny genomes were used for allele screening.
Samarakoon et al. BMC Genomics 2011 12:116 doi:10.1186/1471-2164-12-116