Table 2

Statistical comparison of performances of classifiers trained on normal and without-one-feature morbidity datasets

Missing feature 1

Median AUC [min,max]2

N

W

Wc (two-tailed p = 0.05)3


ppi

0.715 [0.705,0.726]

10

26

8

metin

0.714 [0.707,0.727]

10

26

8

metout

0.713 [0.707,0.729]

10

25

8

regin

0.714 [0.703,0.726]

9

18

6

regout

0.716 [0.705,0.729]

10

26

10

c

0.713 [0.701,0.724]

10

13

8

identicalness

0.711 [0.704,0.727]

10

24

8

cent

0.714 [0.707,0.727]

10

25

8

inbet

0.716 [0.708,0.731]

10

25

8

inbetppi

0.714 [0.707,0.727]

9

21

6

inbetmet

0.714 [0.707,0.728]

9

21

6

inbetreg

0.715 [0.706,0.727]

10

25

8

numtissuesexp4

0.709 [0.701,0.719]

10

7

8*

avegexptec5

0.715 [0.704,0.727]

10

27

8

Unknown

0.713 [0.701,0.725]

10

18

8

Cytoplasm

0.715 [0.706,0.728]

10

26

8

Endoplasmic reticulum

0.716 [0.705,0.727]

10

26

8

Mitochondrion

0.714 [0.706,0.728]

10

24

8

Nucleus

0.715 [0.704,0.728]

10

24

8

Other localization

0.714 [0.704,0.726]

10

21

8

Cellular component

0.714 [0.705,0.727]

9

21

6

Extracellular space

0.710 [0.7,0.723]

10

14

8

Golgi apparatus

0.715 [0.706,0.728]

10

26

8


Median AUC [min,max] for normal datasets: 0.716 [0.706,0.729]


1 See “Methods” and Additional file 1 for a description of features

2 Of 10 datasets

3 According to table of critical values for W in [6]

4 The number of tissues (out of 32) in which the gene is expressed at least 5 transcripts per million (tpm) according to Reverter et al. [33]

5 The average expression in tpm among all the tissues in which the gene is expressed according to Reverter et al. [33]

* Difference statistically significant

Costa et al. BMC Genomics 2010 11(Suppl 5):S9   doi:10.1186/1471-2164-11-S5-S9

Open Data