Additional file 4.

Heparin binding induces a distinct conformation of the occluding loop Structural alignment of the average structures obtained from the MD simulations in alkaline conditions. Color definitions are represented. We represented the occluding loop region in tubes to highlight the distinct conformation adopted by this structural element when catB binds heparin.

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Costa et al. BMC Genomics 2010 11(Suppl 5):S5   doi:10.1186/1471-2164-11-S5-S5