Figure 6.

Allosteric effect of heparin: stabilization of motions in functional regions of catB A) RMS fluctuations of the trajectories in alkaline conditions calculated from projection of the MD trajectories onto the 5 principal components. B) Visualization of the motions of the active site and occluding loop provided by the first two principal components. The directions and amplitudes of the motions are represented by red arrows. C) Concerted motions in the R-domain complex. The regions with large amplitude movements are represented in yellow. The representation of directions and amplitudes is the same as B.

Costa et al. BMC Genomics 2010 11(Suppl 5):S5   doi:10.1186/1471-2164-11-S5-S5