Electrostatic surface of catB in distinct protonation states reveals two possible heparin binding sites The electrostatic surface of catB using protonation states corresponding to acidic and alkaline pH conditions. Blue, red, and white indicate positively charged regions, negative areas and neutral regions, respectively, with the scale indicating ± kbT/ec, where kb is the Boltzmann constant, T is the temperature and ec is the charge of one electron. The heparin binding sites correspond to the basic regions localized in each domain.
Costa et al. BMC Genomics 2010 11(Suppl 5):S5 doi:10.1186/1471-2164-11-S5-S5