This article is part of the supplement: Proceedings of the 5th International Conference of the Brazilian Association for Bioinformatics and Computational Biology (X-meeting 2009)

Open Access Proceedings

Tumor and reproductive traits are linked by RNA metabolism genes in the mouse ovary: a transcriptome-phenotype association analysis

Ulises Urzúa1*, Garrison A Owens2, Gen-Mu Zhang3, James M Cherry2, John J Sharp4 and David J Munroe2

Author Affiliations

1 Laboratorio de Genómica Aplicada, ICBM, Universidad de Chile, Independencia 1027, Santiago, Chile

2 Laboratory of Molecular Technology, SAIC-NCI Frederick, 915 Tollhouse Avenue, Suite 211, Frederick, MD 21701, USA

3 Laboratory Animal Sciences Program, SAIC-NCI Frederick, Frederick, MD 21702, USA

4 Center for Comparative Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA

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BMC Genomics 2010, 11(Suppl 5):S1  doi:10.1186/1471-2164-11-S5-S1

Published: 22 December 2010

Additional files

Additional file 1:

Contains: Table 1: Detailed microarray ratios and Q-PCR results of selected transcripts. Table 2: Functional analysis of genes correlated to all phenotypes. Table 3: Gene Ontology profile of genes differentially expressed between SWR and the remaining three strains. Figure 1: Summary of statistical tests among ovarian transcriptional profiles of four mouse strains.

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Additional file 2:

Contains the complete, loess normalized dataset for 14,586 transcripts.

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Additional file 3:

Contains results for all 145 clones correlated both to OTF and NL in mouse ovaries.

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Additional file 4:

Functional profile of transcripts correlated both to OTF and NL in the mouse ovary

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