Radicality of amino acid substitutions in single copy and duplicated genes. A: mean absolute change of polarity between destination and source amino acids in gene families with different molecular function. B: mean exchangeability . Colours as on Fig. 3. Insets: comparison of ambiguous and unambiguous substitutions.
Yampolsky and Bouzinier BMC Genomics 2010 11(Suppl 4):S10 doi:10.1186/1471-2164-11-S4-S10