Table 3

Representative cellular processes related to parasite specific lifestyle that are commonly present in six Plasmodium genomes.

Function description

Examples of GO classes

Orthologous families


Cell Cycle

GO:0000079 (Regulation of cyclin-dependent protein kinase activity)

ORTHOMCL1356

ORTHOMCL2659


GO:0051726 (regulation of cell cycle)

ORTHOMCL703

ORTHOMCL2129

ORTHOMCL2139

ORTHOMCL3332

ORTHOMCL93

ORTHOMCL1497

ORTHOMCL2030

ORTHOMCL3034


GO:0045836 (positive regulation of meiosis)

ORTHOMCL1572


GO:0007049 (cell cycle)

ORTHOMCL3532

ORTHOMCL1160


GO:0000082 (G1/S transition of mitotic cell cycle)

ORTHOMCL3162


Signal transduction

GO:0007266 (Rho protein signal transduction)

ORTHOMCL2354


GO:0007165 (signal transduction)

ORTHOMCL3462

ORTHOMCL3526

ORTHOMCL3426

ORTHOMCL1645

ORTHOMCL710


GO:0007186 (G-protein coupled receptor protein signaling pathway)

ORTHOMCL3024


GO:0008426 (protein kinase C inhibitor activity)

ORTHOMCL2343


Response to environmental challenges

GO:0006979 (response to oxidative stress)

ORTHOMCL2680

ORTHOMCL602

ORTHOMCL2542

ORTHOMCL1549

ORTHOMCL2530

ORTHOMCL1476

ORTHOMCL3291

ORTHOMCL3446

ORTHOMCL2315


GO:0006950 (response to stress)

ORTHOMCL3208


GO:0009408 (response to heat)

ORTHOMCL2452

ORTHOMCL2633

ORTHOMCL112

ORTHOMCL237

ORTHOMCL702

ORTHOMCL803

ORTHOMCL1088

ORTHOMCL1813

ORTHOMCL3347

ORTHOMCL1486

ORTHOMCL2019

ORTHOMCL3266

ORTHOMCL700


Pathogenesis

GO:0009405 (pathogenesis)

ORTHOMCL2797


GO:0030260 (entry into host cell)

ORTHOMCL106

ORTHOMCL15

ORTHOMCL2196

ORTHOMCL2303


GO:0042493 (response to drug)

ORTHOMCL3437

ORTHOMCL780


GO:0020035 (cytoadherence to microvasculature, mediated by parasite protein)

ORTHOMCL361

ORTHOMCL41


Cai et al. BMC Genomics 2010 11(Suppl 3):S13   doi:10.1186/1471-2164-11-S3-S13

Open Data