Table 10

Estimated disorder frequencies in the human proteome with IUPred long.

IUPred long threshold

minimum length to consider region as disordered

% of sequences with disorder

% of disordered residues


0.50

0

82.6

26.7

0.50

10

62.0

22.8

0.50

30

38.8

17.5

0.54

0

78.8

23.3

0.54

10

57.3

19.7

0.54

30

34.9

14.9


A subset with 56915 non-redundant sequences (< 98% identity) from the human IPI v3.54 database was used to estimate frequencies of disordered residues and sequences with disorder predicted by IUPred long at different thresholds (0.5 ... default; 0.54 ... estimated 5% false positive rate)

Sirota et al. BMC Genomics 2010 11(Suppl 1):S15   doi:10.1186/1471-2164-11-S1-S15

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