Table 5

Lysine and arginine methylation motifs.

Gene name

Swiss-Prot accession

Methylation sitea

Motifb


MK motif

Gcd10p

P41814

meth-K4362

RGKLHPLMT

    M
    K
GGGGYLMWCH

Pfk2p

P16862

meth-K1801

HSYTDLAYR

    M
    K
TTDTYPSLPK

Rpl23Ap

P04451

dimeth-K1101

GVIANPKGE

    M
    K
GSAITGPVGK

Rps17Ap

P02407

dimeth-K592

KIAGYTTHL

    M
    K
RIQKGPVRGI

Rvb2p

Q12464

meth-K4122

LISVAQQIA

    M
    K
RKNNTVEVED

Ura7p

P28274

dimeth-K282

VLASSTGML

    M
    K
TLGLKVTSIK

Uso1p

P25386

meth-K1192

NGKYPSPLV

    M
    K
QEKEQVDQFS

RGx or RxG motif

Ecm29p

P38737

dimeth-R11122

LAKSSALWSS

    R
    KG
IAFGLGAI

Gus1p

P46655

dimeth-R3712

IYRCNLTPHH

    R
    TG
STWKIYPT

Rpl27Bp

P38706

dimeth-R152

LKAGKVAVVV

    R
    GR
YAGKKVVI

Rpl4Ap

P10664

dimeth-R842

IPRVGGGGTG

    R
    SG
QGAFGNMC

Rps11Bp

P26781

dimeth-R672

KCPFTGLVSI

    R
    GK
ILTGTVVS

Tdh3p

P00359

dimeth-R112

MVRVAINGFG

    R
    IG
RLVMRIAL

Tub2p

P02557

dimeth-R3182

GRYLTVAAFF

    R
    GK
VSVKEVED

WxxxR and/or GxxR motif

Cdc11p

P32458

dimeth-R352

VMIVGQS

    GSG
    R
STFINTLCGQ

Ecm29p

P38737

meth-R5422

ARLFNI

    WGTV
    R
TNRFDIIEES

Fks1p

P38631

meth-R9462, dimeth-R9462

TLRTRI

    WASL
    R
SQTLYRTISG

Fks1p

P38631

dimeth-R15272

YHRNSWI

    GYV
    R
MSRARITGFK

Rpl4Ap

P10664

dimeth-R842

IPRVGGG

    GTG
    R
SGQGAFGNMC

Rpl7Ap, Rpl7Bp

P05737

meth-R2182

SNPSGG

    WGVP
    R
KFKHFIQGGS

Rsc30p

P38781

meth-R6922

SIKSFSS

    GNN
    R
FHSNGKEFLF

Tdh3p

P00359

dimeth-R112

MVRVAIN

    GFG
    R
IGRLVMRIAL


a: Evidence for the presence of the methylation site on this protein 1: Swiss-Prot, 2: methylation site confirmed by FindMod analysis

b: Methylation site matching the specified motif is underlined, the methylation site is highlighted in bold.

Pang et al. BMC Genomics 2010 11:92   doi:10.1186/1471-2164-11-92

Open Data