Table 1

Mkrn1- and mkrn2-related retro(pseudo)genes in human and mouse genomes.

Location

Gene names

Annotation

EST support


Human mkrn1


Hsa7 140.152.840-140.179.369

MKRN1, RNF61, ENSG00000133606

source protein-coding gene with introns

expressed in many adult tissues


Hsa15 23.810.454-23.813.164

MKRN3, D15S9, MGC88288, RNF63, ZFP127, ZNF127

protein-coding retrogene

EST data for blood, brain, esophagus, liver, placenta, prostate and skin


Hsa1 43.356.765-43.358.101

ENSG00000237090, RP11-342M1.6, MKRNP4*

retropseudogene

no EST support


Hsa2 153.707.170-153.707.338

ENSG00000234932

retropseudogene

no EST support


Hsa3 130.647.120-130.646.607

located in intron of ATP2C1 (ENSG00000017260), MKRNP5*

retropseudogene

no EST support


Hsa9 99.488.172-99.489.449

RP11-535M15.2, ENSG00000233820, makorin ring finger protein 1 pseudogene

retropseudogene

no EST support


Hsa12 88.177.249-88.178.345

MKRN9P MKRNP6, MKRN5, MKRN9, RNF65, ZNF127L3, ENSG00000213267

retropseudogene

no EST support


Hsa12 88.176.895-88.176.996

ENSG00000237340

retropseudogene

Hypothalamus BI457939.1


Hsa20 45.092.541-45.093.763

MKRNP3, ENSG00000225849, RP5-981L23.2, DB295917.1

retropseudogene

no EST support


HsaX 40.693.508-40.697.060

MKRNP5, MKRN4, ZNF127-Xp, ZNF127L1, ZNF-Xp, ENSG00000238222, OTTHUMG00000024109,

partially processed retropseudogene

no EST support


HsaX 73.380.895-73.382.363

MKRNP1, ZNF127-Xq, RP13-204A15.3, ENSG00000224430

retropseudogene

no EST support


HsaX 91.627.539-91.627.653

inside intron of PCDH11X

retro(pseudo?)gene, very short but intact ORF

no EST support


HsaY 5.352.120-5.352.234

inside intron of PCDH11Y

retro(pseudo?)gene, very short but intact ORF

no EST support


Mouse mkrn1


Mmu6 39.347.803-39.370.437

Mkrn1, ENSMUSG00000029922, NM_018810

source protein-coding gene with introns

widely expressed in adult tissue with strong expression in adult gonad and embryonic nervous system [ref. [30] and EST data]


Mmu7 69.563.293-69.564.927

Mkrn3, ENSMUSG00000070527

protein-coding retrogene

EST data for brain, inner ear, pancreas, spinal cord and thymus


Mmu2 27.338.749-27.339.289

no annotation

newly annotated retropseudogene

no EST support


Mmu3 129.843.302-129.845.025

no annotation

retropseudogene

no EST support


Mmu5 89.267.034-89.268.427

Mkrn1-ps1, AC160533.6, ENSMUSG00000082389, AF494488

retropseudogene

no EST support


Mmu5 111.334.263-111.334.760

AC121934.4 (ENSMUSG00000081104), OTTMUSG00000028665

retropseudogene

no EST support


Mmu13 77.911.041-77.911.846

in Intron of 1110033M05Rik (ENSMUSG00000064138)

retropseudogene

no EST support


MmuX 54.923.521-54.923.664

RP23-435H13.3, OTTMUSG00000017520

retropseudogene

no EST support


Mouse mkrn2


Mmu6 115.551.979-115.568.688

Mkrn2, ENSMUSG00000000439, C81377; 2610002L04Rik

source protein-coding gene with introns

EST data for several tissue


Mmu10 30.093.050-30.095.334

no annotation

retropseudogene

no EST support


MmuX 13.504.413-13.506.637

BX005215.13, ENSMUSG00000082736, RP23-280F9.1, OTTMUSG00000016911

Partially processed retropseudogene (contains only 2 introns)

no EST support


Mmu2 106.753.075-106.754.515

no annotation

retropseudogene

no EST support


Positions are based on human GRCh37 and mouse NCBIM37 assemblies. Gene names marked with "*" refer to reference [4].

Böhne et al. BMC Genomics 2010 11:721   doi:10.1186/1471-2164-11-721

Open Data