Additional file 1.
miRNA profiling of the adult mouse retina, RPE, cornea and lens. Heat-map of two-way hierarchical clustering analysis for 285 miRNAs with Delta Log2 median ratio ΔLMR ≥ 0.5 in at least one of the samples (panel A). Only miRNAs with values across all samples were considered for the analysis. Colors indicate relative expression compared to the mean for each miRNA in the entire eye: red color represents an expression level above mean, green color represents expression lower than the mean. The complete set of nodes can be seen. The 5 clusters (A-E) obtained at the five-node level are delimited by green brackets. The 25 miRNA sub-clusters selected are highlighted with blue lines. The clustering of the tissues analyzed based on their miRNA content is shown by the horizontal dendrogram in panel B. sc: sub-cluster.
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Karali et al. BMC Genomics 2010 11:715 doi:10.1186/1471-2164-11-715