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Open Access Research article

Comparative transcriptome profiling analyses during the lag phase uncover YAP1, PDR1, PDR3, RPN4, and HSF1 as key regulatory genes in genomic adaptation to the lignocellulose derived inhibitor HMF for Saccharomyces cerevisiae

Menggen Ma and Z Lewis Liu*

Author Affiliations

Bioenergy Research Unit, National Center for Agricultural Utilization Research, USDA-ARS, Peoria, IL USA

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BMC Genomics 2010, 11:660  doi:10.1186/1471-2164-11-660

Published: 24 November 2010

Additional files

Additional file 1:

Differential expression of significantly affected genes of Saccharomyces cerevisiae in response to HMF challenges during the lag phase.

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Additional file 2:

Gene Ontology (GO) categories and terms for significantly repressed genes by HMF (30 mM) challenge in Saccharomyces cerevisiae NRRL Y-12632.

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Additional file 3:

Regulatory interaction networks for repressed genes under HMF stress.

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Additional file 4:

Protein binding motifs and binding elements for significantly induced genes by HMF challenge during the lag phase in Saccharomyces cerevisiae.

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Additional file 5:

Primers used for mRNA expression analysis for Saccharomyces cerevisiae by real-time qRT-PCR using SYBR Green I.

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Open Data