Sex specific regulation of muscle gene transcription induced by resistance exercise. a. Repression of negative regulators of mTOR signaling in male muscle. b. Up-regulation of TGF-beta signaling in female muscle. Y axis represents fold changes (log2): Positive values indicate up-regulation post exercise in exercised vs. rested muscle, and negative values indicate down-regulation. * Significantly different from the rested muscle (p < 0.005); # trend towards a differential expression in exercised vs. rested muscle (p < 0.05).
Liu et al. BMC Genomics 2010 11:659 doi:10.1186/1471-2164-11-659