Conservation of PRR20 in primates. Alignment of the predicted amino-acid sequence of the PRR20 protein from great apes and macaque. The primate is listed to the left, as is the amino-acid residue number. Identical amino-acids are highlighted in black, amino-acids with similar properties are black letters shaded grey and divergent residues are black letters on a white background. Gaps in the alignment are represented by dashes. Alignments were prepared using ClustalW2 http://www.ebi.ac.uk/Tools/clustalw2/index.html webcite and the output used to generate the shaded version shown using the Boxshade 3.21 server http://www.ch.embnet.org/software/BOX_form.html webcite. Chimp sequence obtained from Pan troglodytes genome assembly (CGSC 2.1/panTro2) using the UCSC genome browser http://genome.ucsc.edu/ webcite. Gorilla sequence obtained from Gorilla gorilla genome assembly (gorGor3) using the Ensembl genome browser http://www.ensembl.org/index.html webcite. Orangutan sequence obtained from a complete Pongo abelii BAC clone (Accession Number AC206922). Macaque sequence obtained from Macaca mulatta genome assembly (rheMac2) using the UCSC genome browser.
Tremblay et al. BMC Genomics 2010 11:632 doi:10.1186/1471-2164-11-632