Table 4

The Varroa destructor glycolysis/gluconeogenesis pathway is well represented in the genome sequence survey

Glycolysis/gluconeogesis enzyme

KEGG ID

Annotated in A. gambiae

Annotated in I. scapularis

Closest contig match in the V. destructor assembly (BLASTX)

Strand

Start

Stop

E-value


6-phosphofructokinase

K00850

X

x

VDK00166959

+

274

486

6.00E-027


acetyl-CoA synthetase

K01895

X

x

VDK00052872

-

313

1554

3.00E-085


aldehyde dehydrogenase

K00128

X

x

VDK00013090

+

2385

3224

1.00E-138


dihydrolipoamide dehydrogenase

K00382

X

x

VDK00011534

-

343

917

1.00E-020


enolase

K01689

X

x

VDK00029529

-

752

2211

7.00E-143


fructose-1,6-bisphosphatase

K03841

X

x

VDK00132162

+

158

355

1.00E-023


fructose-bisphosphate aldolase

K01623

X

x

VDK00012888

+

801

2121

1.00E-073


glucose-6-phosphate isomerise

K01810

X

x

VDK00034893

+

2

145

6.00E-018


glyceraldehyde 3-phosphate dehydrogenase

K00134

X

x

VDK00020468

-

142

2477

2.00E-077


hexokinase

K00844

X

x

VDK00023511

-

313

1522

2.00E-094


phosphoenolpyruvate carboxykinase

K01596

X

x

VDK00063370

-

1166

1684

1.00E-038


phosphoglucomutase

K01835

X

x

VDK00033184

-

236

478

3.00E-024


phosphoglycerate kinase

K00927

X

x

VDK00052433

+

351

1229

4.00E-032


phosphoglycerate mutase

K01834

X

x

VDK00033074

-

257

2550

5.00E-031


pyruvate dehydrogenase E1 component, subunit alpha

K00161

X

x

VDK00079694

-

2

1382

8.00E-043


pyruvate dehydrogenase E1 component, subunit beta

K00162

X

x

VDK00041927

-

527

2110

2.00E-020


pyruvate dehydrogenase E2 component

K00627

X

x

VDK00062508

-

165

416

4.00E-033


pyruvate kinase

K00873

X

x

VDK00096436

-

676

1131

4.00E-067


S-(hydroxymethyl)glutathione dehydrogenase

K00121

X

x

VDK00003663

-

1731

2700

4.00E-125


glucose-6-phosphate 1-epimerase

K01792

X

x


triosephosphate isomerise

K01803

X

x


aldose 1-epimerase

K01785

X


L-lactate dehydrogenase

K00016

X


Putative pathway components listed below were identified by BLASTX, using KEGG-annotated components [40] from Anopheles gambiae and Ixodes scapularis as search queries.

Cornman et al. BMC Genomics 2010 11:602   doi:10.1186/1471-2164-11-602

Open Data