Figure 1.

Disease penetrance models. Penetrance models used to simulate epistasis between two SNPs. Allele frequencies are denoted with p and q. For example, model 1 specifies that 10% of individuals with genotypes AABb, AaBB, Aabb or aaBb and none of individuals with other genotypes have the disease.

Toplak et al. BMC Genomics 2010 11:58   doi:10.1186/1471-2164-11-58
Download authors' original image