Open Access Highly Accessed Research article

Deep sequencing of small RNA libraries reveals dynamic regulation of conserved and novel microRNAs and microRNA-stars during silkworm development

Guru Jagadeeswaran1, Yun Zheng2, Niranji Sumathipala3, Haobo Jiang3, Estela L Arrese1, Jose L Soulages1, Weixiong Zhang24 and Ramanjulu Sunkar1*

Author Affiliations

1 Department of Biochemistry and Molecular Biology, Oklahoma State University, Stillwater, OK 74078, USA

2 Department of Computer Science and Engineering, Washington University in St. Louis, St Louis MO 63130, USA

3 Department of Entomology and Plant Pathology, Oklahoma State University, Stillwater, OK 74078, USA

4 Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA

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BMC Genomics 2010, 11:52  doi:10.1186/1471-2164-11-52

Published: 20 January 2010

Additional files

Additional file 1:

Predicted targets for the newly identified miRNAs and miRNA*s in silkworm. For each predicted target, accession number, annotation and hit scores are provided.

Format: XLS Size: 197KB Download file

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Additional file 2:

Top 20 most abundantly expressed miRNAs in silkworm during different developmental stages. Proportion of reads recovered for miRNAs in each of the four developmental stages, i.e., feeding larvae, spinning larvae, pupae and moth are provided.

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Open Data