Empirical cumulative distribution functions (ECDF) of enrichment P values. The P values show the degree of enrichment among high-scoring yeast eQTL for genes that map to the same KEGG pathway as the target gene (A) and genes that map to the same pathway as the known transcription factors for the target gene (B). In both scenarios RFSF achieved the best performance in recovering loci enriched for pathway-related genes.
Michaelson et al. BMC Genomics 2010 11:502 doi:10.1186/1471-2164-11-502